Management of bone defects using the Masquelet technique of induced membrane

Abstract

Introduction: Extensive bone defects are mostly caused by trauma, bone infection or bone tumours. The treatment is one of the most challenging issues of musculoskeletal surgery. Nowadays we have several techniques to deal with this problem. One of them is a two staged procedure described by Alain Masquelet, based on the principle of a foreign body-induced membrane with an autologous bone graft. The membrane, induced by a cement spacer, closes the defect and prevents resorption of the bone graft. In this paper we share our experience with this method.
Methods: We retrospectively analysed 10 patients who had been treated at our department between years 2012 and 2020. In addition to basic epidemiological data, we also collected data concerning the mechanism of injury, size of the defect, presence of infection and the infectious agent, type of spacer used and its retention, type of bone stabilization, time to full load, and time of full consolidation.
Results: We evaluated 10 patients with bone defects (5 of traumatic and 5 of infectious origin) operated at our department. Optimal healing free of complications was achieved in 50% of patients, and together with those where the 2nd phase had to be repeated, the success rate was 70%. Observed complications included two refractures, two cases of infection and one case of prolonged healing.
Conclusions: Bone defect management using the modified...